(S)-2-AMINO-3-(3,4-DIFLUORO-PHENYL)-PROPIONIC ACID

(S)-2-AMINO-3-(3,4-DIFLUORO-PHENYL)-PROPIONIC ACID - Names and Identifiers

Name	3,4-Difluoro-L-phenylalanine
Synonyms	H-PHE(3,4-F 2)-OH H-PHE(3,4-DIF)-OH L-3,4-DIFLUOROPHE H-D-PHE(M,P-F2)-OH RARECHEM BK PT 0121 H-3,4-DIFLUORO-L-PHE-OH L-3,4-DIFLUOROPHENYLALANINE l-3,4-difluorophenylalanine 3,4-Difluoro-L-phenylalanine (S)-2-AMINO-3-(3,4-DIFLUORO-PHENYL)-PROPIONIC ACID
CAS	31105-90-5
EINECS	200-528-9
InChI	InChI=1/C9H9F2NO2/c10-6-2-1-5(3-7(6)11)4-8(12)9(13)14/h1-3,8H,4,12H2,(H,13,14)/t8-/m0/s1

(S)-2-AMINO-3-(3,4-DIFLUORO-PHENYL)-PROPIONIC ACID - Physico-chemical Properties

Molecular Formula	C9H9F2NO2
Molar Mass	201.17
Density	1.379±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	311.9±42.0 °C(Predicted)
Flash Point	142.5°C
Vapor Presure	0.000234mmHg at 25°C
pKa	2.16±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.536
MDL	MFCD01075125

(S)-2-AMINO-3-(3,4-DIFLUORO-PHENYL)-PROPIONIC ACID - Risk and Safety

Hazard Symbols

Xi - Irritant

(S)-2-AMINO-3-(3,4-DIFLUORO-PHENYL)-PROPIONIC ACID - Introduction

3,4-Difluoro-L-phenylalanine is an amino acid derivative with the formula C9H10F2NO2.

Nature:
3,4-Difluoro-L-phenylalanine is a solid and has the form of a white crystal or a crystalline powder. It has chirality and exists in both L-and D-configurations, but usually only the L-configuration is used. It has a melting point of about 205-207°C and has good solubility and can be dissolved in water.

Use:
3,4-Difluoro-L-phenylalanine is commonly used in pharmaceutical research and organic synthesis. It can be used as chiral reagents, drug partitioning agents and drug intermediates. In addition, it can be used for protein engineering and conformational studies in biochemical research.

Preparation Method:
Generally, the synthesis method of 3,4-Difluororo-L-phenylalanine involves reacting alanine with 3,4-difluorobenzoic acid, and then going through appropriate preparation and separation steps to obtain the desired product. The specific synthesis method can be improved and optimized according to laboratory conditions and requirements.

Safety Information:
The safety information of 3,4-Difluoro-L-phenylalanine shall be subject to the safety measures and requirements required for actual operation in the laboratory. Generally speaking, it can be regarded as a low-toxic compound, but it is still necessary to pay attention to its irritation to the skin, eyes and mucous membranes. When in use, wear appropriate protective equipment, such as gloves, goggles and protective clothing, and operate in a well-ventilated environment. At the same time, avoid contact with strong oxidants and strong acids to prevent dangerous reactions.

Please note that when using and studying 3,4-Difluoro-L-phenylalanine, corresponding safety measures must be taken according to specific experimental conditions and laboratory guidelines.

Last Update：2024-04-09 21:54:55